Article

A new SARS-CoV-2 variant poorly detected by RT-PCR on nasopharyngeal samples, with high lethality

2021-05-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> In early January 2021, an outbreak of nosocomial cases of COVID-19 emerged in Western France, with RT-PCR tests repeatedly negative on nasopharyngeal samples but positive on lower respiratory tract samples. Whole genome sequencing (WGS) revealed a new variant, currently defining a novel SARS-CoV-2 lineage: B.1.616. In March, WHO classified this variant as ‘under investigation’...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6ed1d014-e053-52a7-9465-33d0cf88ba91
DOI: 10.1101/2021.05.05.21256690

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A new SARS-CoV-2 variant poorly detected by RT-PCR on nasopharyngeal samples, with high lethalityDOI 10.1101/2021.05.05.21256690Read

A New SARS-CoV-2 Variant Poorly Detected by RT-PCR on Nasopharyngeal Samples, with High LethalitySemantic proximity Read

Rapid SARS-CoV-2 variant monitoring using PCR confirmed by whole genome sequencing in a high-volume diagnostic laboratorySemantic proximity Read

SARS CoV-2 Genomic Characteristics and Clinical Impact of SARS-CoV-2 Viral Diversity in Critically Ill COVID-19 Patients: A Prospective Multicenter Cohort StudySemantic proximity Read

Clinical and Virological Features of SARS-CoV-2 Variants of Concern: A Retrospective Cohort Study Comparing B.1.1.7 (Alpha), B.1.315 (Beta), and B.1.617.2 (Delta)Semantic proximity Read

Limitation of Screening of Different Variants of SARS-CoV-2 by RT-PCRSemantic proximity Read

Unveiling the emergence of SARS-CoV-2 JN.1 sub-variant: Insights from the first cases at Charles Nicolle Hospital, Tunisia.Semantic proximity Read

SARS-CoV-2 R.1 lineage variants prevailed in Tokyo in March 2021Semantic proximity Read

Evaluation of a Rapid and Accessible RT-qPCR Approach for SARS-CoV-2 Variant of Concern IdentificationSemantic proximity Read

SARS-CoV2 RT-PCR assays: In vitro comparison of 4 WHO approved protocols on clinical specimens and its implications for real laboratory practice through variant emergenceSemantic proximity Read

COVID-19 cases from the first local outbreak of SARS-CoV-2 B.1.1.7 variant in China presented more serious clinical features: a prospective, comparative cohort studySemantic proximity Read

Influence of SARS-CoV-2 variants on COVID-19 epidemiological and clinical profiles: a comparative analysis of two waves of casesSemantic proximity Read

SARS-CoV-2 N501Y introductions and transmissions in Switzerland from beginning of October 2020 to February 2021 – implementation of Swiss-wide diagnostic screening and whole genome sequencingSemantic proximity Read