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Article

Generation of catecholaminergic polymorphic ventricular tachycardia patient-specific induced pluripotent stem cell line.

Stem cell research - 1 Apr 2022

Colombani Sarah, Bernardin Albin A, Vincenti Marie, Amédro Pascal, Desprat Romain, Bernex Florence, Lemaitre Jean-Marc, Pasquié Jean-Luc, Lacampagne Alain, Meli Albano C

Abstract excerpt

Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a genetic disorder characterized by ventricular tachycardia, that can cause the heart to stop beating leading to death. The prevalence is 1/10.000 and in approximately 60% of cases, the syndrome can be due to a mutation of the cardiac ryanodine receptor gene (RyR2). We derived an induced pluripotent stem cell (iPSC) line from an 11-year-old patient...

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Source

Identifiers

PMID: 35245853
DOI: 10.1016/j.scr.2022.102727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Generation of catecholaminergic polymorphic ventricular tachycardia patient-specific induced pluripotent stem cell line.PMID 35245853Read ↗

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