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Article

Generation of two induced pluripotent stem cell lines from catecholaminergic polymorphic ventricular tachycardia patients carrying RYR2 mutations.

Stem cell research - 1 Jun 2023

Kong Xiaohui, Belbachir Nadjet, Zeng Wenshu, Yan Christopher D, Navada Sai, Perez Marco V, Wu Joseph C

Abstract excerpt

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a congenital arrhythmic syndrome caused by the RYR2 gene encoded ryanodine receptor. Mutations on RYR2 are commonly associated with ventricular tachycardia after adrenergic stimulation, leading to lethal arrhythmias and sudden cardiac death. We generated two human induced pluripotent stem cell (iPSC) lines from CPVT affected patients carrying single...

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Share to Arrhythmias, Cardiac
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Ryanodine Receptor Calcium Release Channel

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Identifiers

PMID: 37210947
DOI: 10.1016/j.scr.2023.103111
PMCID: PMC11059235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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