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Genetic variants in choline metabolism pathway are associated with the risk of bladder cancer in the Chinese population.

Archives of toxicology - 1 Jun 2022

Han Zhichao, Gu Jingjing, Xin Junyi, Liu Hanting, Wu Yanling, Du Mulong, Chu Haiyan, Liu Yadong, Zhang Zhengdong

Abstract excerpt

Choline metabolism alteration is considered as a metabolic hallmark in cancer, reflecting the complex interactions between carcinogenic signaling pathways and cancer metabolism, but little is known about whether genetic variants in the metabolism pathway contribute to the susceptibility of bladder cancer. Herein, a case-control study comprising 580 patients and 1,101 controls was carried out to analyze the...

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PMID: 35237847
DOI: 10.1007/s00204-022-03258-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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