Article
Use of mycobacterial interspersed repetitive unit-variable-number tandem repeat typing to examine genetic diversity of Mycobacterium tuberculosis in Singapore.
Journal of clinical microbiology - 1 May 2004
Sun Yong-Jiang, Bellamy Richard, Lee Ann S G, Ng Sze Ta, Ravindran Sindhu, Wong Sin-Yew, Locht Camille, Supply Philip, Paton Nicholas I
Abstract excerpt
Strain typing using variable-number tandem repeats of mycobacterial interspersed repetitive units (MIRU-VNTR) is a powerful tool for studying the epidemiology and genetic relationships of Mycobacterium tuberculosis isolates. For this study, isolates from 291 patients in Singapore were genotyped by this method. One hundred sixty-six distinct MIRU-VNTR patterns were detected. One hundred sixty-two strains were...
Topics
- Alleles
- Bacterial Typing Techniques
- Base Sequence
- DNA Primers
- DNA, Bacterial
- Genetic Variation
- Humans
- Interspersed Repetitive Sequences
- Minisatellite Repeats
- Molecular Epidemiology