Article
Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population.
Alcoholism, clinical and experimental research - 1 May 2018
Gelernter Joel, Zhou Hang, Nuñez Yaira Z, Mutirangura Apiwat, Malison Robert T, Kalayasiri Rasmon
Abstract excerpt
BACKGROUND: Alcohol use (both quantity and dependence) is moderately heritable, and genomewide association studies (GWAS) have identified risk genes in European, African, and Asian populations. The most reproducibly identified risk genes affect alcohol metabolism. Well-known functional variants at the gene encoding alcohol dehydrogenase B and other alcohol dehydrogenases affect risk in European and African...
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