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Article

Comprehensive analysis of SPAG1 expression as a prognostic and predictive biomarker in acute myeloid leukemia by integrative bioinformatics and clinical validation.

BMC medical genomics - 28 Feb 2022

Gu Yu, Chu Ming-Qiang, Xu Zi-Jun, Yuan Qian, Zhang Ting-Juan, Lin Jiang, Zhou Jing-Dong

Abstract excerpt

BACKGROUND: Recently, an increasing number of studies have reported that sperm-associated antigen (SPAG) proteins play crucial roles in solid tumorigenesis, and may serve as potentially helpful biomarkers for cancer diagnosis and prognosis. However, very few studies systematically investigated the expression of SPAG family members and their clinical significance in acute myeloid leukemia (AML). METHODS: The...

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Identifiers

PMID: 35227274
DOI: 10.1186/s12920-022-01193-0
PMCID: PMC8886923

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