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Metabolomic Profiling Reveals That 5-Hydroxylysine and 1-Methylnicotinamide Are Metabolic Indicators of Keloid Severity

9 Feb 2022

Abstract excerpt

Background: Keloid is a skin fibroproliferative disease with unknown pathogenesis. Metabolomics provides a new perspective for revealing biomarkers related to metabolites and their metabolic mechanisms. Method: Metabolomics and transcriptomics were used for data analysis. Quality control of the data was performed to standardize the data. Principal component analysis (PCA), PLS-DA, OPLS-DA, univariate analysis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35222522
DOI: 10.3389/fgene.2021.804248

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