Article
Intravenous Immunoglobulin Therapy Restores the Quantity and Phenotype of Circulating Dendritic Cells and CD4+ T Cells in Children With Acute Kawasaki Disease.
Frontiers in immunology - 1 Jan 2022
Wang Nana, Chen Zhongyue, Zhang Fan, Zhang Qianwen, Sun Ling, Lv Haitao, Wang Bo, Shen Jie, Zhou Xufang, Chen Feiyan, Zhang Binwei, Meng Lijun, Zhou Huiting, Bai ZhenJiang, Huang Jie
Abstract excerpt
Background: Intravenous immunoglobulin (IVIG) showed its therapeutic efficacy on Kawasaki disease (KD). However, the mechanisms by which it reduces systemic inflammation are not completely understood. Dendritic cells (DCs) and T cells play critical roles in the pathogenic processes of immune disorders. Assessing the quantity of DC subsets and T cells and identifying functional molecules present on these cells,...
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