Article
Kawasaki disease: aetiopathogenesis and therapeutic utility of intravenous immunoglobulin.
Autoimmunity reviews - 1 Apr 2010
Galeotti Caroline, Bayry Jagedeesh, Kone-Paut Isabelle, Kaveri Srinivas V
Abstract excerpt
Kawasaki disease (KD) is an acute febrile childhood vasculitis, associated with the development of coronary artery abnormalities in 25-30% of untreated patients. The aetiopathogenesis is not well known but it is accepted that an undefined infectious trigger in genetically predisposed individuals results in the disease. KD is characterized by an endothelial cell injury, which could be due to abnormal cytokine...
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