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Article

Prognostic impact of genetic alterations and methylation classes in meningioma.

Brain pathology (Zurich, Switzerland) - 1 Mar 2022

Berghoff Anna S, Hielscher Thomas, Ricken Gerda, Furtner Julia, Schrimpf Daniel, Widhalm Georg, Rajky Ursula, Marosi Christine, Hainfellner Johannes A, von Deimling Andreas, Sahm Felix, Preusser Matthias

Abstract excerpt

Meningiomas are classified based on histological features, but genetic and epigenetic features are emerging as relevant biomarkers for outcome prediction and may supplement histomorphological evaluation. We investigated meningioma-relevant mutations and their correlation with DNA methylation clusters and patient survival times. Formalin-fixed and paraffin-embedded samples of 126 meningioma patients (WHO grade I...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35213082
DOI: 10.1111/bpa.12970
PMCID: PMC8877750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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