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Article

The Difference in the Proportions of Deleterious Variations within and between Populations Influences the Estimation of FST.

Genes - 22 Jan 2022

Subramanian Sankar

Abstract excerpt

Estimating the extent of genetic differentiation between populations is an important measure in population genetics, ecology and evolutionary biology. The fixation index, or FST, is an important measure, which is routinely used to quantify this. Previous studies have shown that the FST estimated for selectively constrained regions was significantly lower than that estimated for neutral regions. By deriving the...

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PMID: 35205239
DOI: 10.3390/genes13020194
PMCID: PMC8872184

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