Article
Estimating and interpreting FST: the impact of rare variants.
Genome research - 1 Sept 2013
Bhatia Gaurav, Patterson Nick, Sankararaman Sriram, Price Alkes L
Abstract excerpt
In a pair of seminal papers, Sewall Wright and Gustave Malécot introduced FST as a measure of structure in natural populations. In the decades that followed, a number of papers provided differing definitions, estimation methods, and interpretations beyond Wright's. While this diversity in methods has enabled many studies in genetics, it has also introduced confusion regarding how to estimate FST from available...
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