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USP15 in Cancer and Other Diseases: From Diverse Functionsto Therapeutic Targets

17 Feb 2022

Abstract excerpt

The process of protein ubiquitination and deubiquitination plays an important role in maintaining protein stability and regulating signal pathways, and protein homeostasis perturbations may induce a variety of diseases. The deubiquitination process removes ubiquitin molecules from the protein, which requires the participation of deubiquitinating enzymes (DUBs). Ubiquitin-specific protease 15 (USP15) is a DUB that...

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PMID: 35203682
DOI: 10.3390/biomedicines10020474

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