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USP5: Comprehensive insights into structure, function, biological and disease-related implications, and emerging therapeutic opportunities

3 Dec 2023

Abstract excerpt

Ubiquitin specific protease 5 (USP5) is a vital deubiquitinating enzyme that regulates various physiological functions by removing ubiquitin chains from target proteins. This review provides an overview of the structural and functional characteristics of USP5. Additionally, we discuss the role of USP5 in regulating diverse cellular processes, including cell proliferation, apoptosis, DNA double-strand damage,...

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PMID: 38049041
DOI: 10.1016/j.mcp.2023.101944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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