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Mitofusin-2 Negatively Regulates Melanogenesis by Modulating Mitochondrial ROS Generation

16 Feb 2022

Abstract excerpt

Inter-organellar communication is emerging as one of the most crucial regulators of cellular physiology. One of the key regulators of inter-organellar communication is Mitofusin-2 (MFN2). MFN2 is also involved in mediating mitochondrial fusion-fission dynamics. Further, it facilitates mitochondrial crosstalk with the endoplasmic reticulum, lysosomes and melanosomes, which are lysosome-related organelles...

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PMID: 35203350
DOI: 10.3390/cells11040701

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