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The major genetic risk factor for severe COVID-19 is associated with protection against HIV

22 Feb 2022

Abstract excerpt

There are genetic risk factors that influence the outcome of COVID-19 [COVID-19 Host Genetics Initiative, Nature 600, 472–477 (2021)]. The major genetic risk factor for severe COIVD-19 resides on chromosome 3 and is inherited from Neandertals [H. Zeberg, S. Pääbo, Nature 587, 610–612 (2020)]. The risk-associated DNA segment modulates the expression of several chemokine receptors, among them CCR5, a coreceptor for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35193979
DOI: 10.1073/pnas.2116435119

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