Phylogeography and transmission of M. tuberculosis in Moldova: A prospective genomic analysis.

doi:10.1371/journal.pmed.1003933

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Article

Phylogeography and transmission of M. tuberculosis in Moldova: A prospective genomic analysis.

PLoS medicine - 1 Feb 2022

Yang Chongguang, Sobkowiak Benjamin, Naidu Vijay, Codreanu Alexandru, Ciobanu Nelly, Gunasekera Kenneth S, Chitwood Melanie H, Alexandru Sofia, Bivol Stela, Russi Marcus, Havumaki Joshua, Cudahy Patrick, Fosburgh Heather, Allender Christopher J, Centner Heather, Engelthaler David M, Menzies Nicolas A, Warren Joshua L, Crudu Valeriu, Colijn Caroline, Cohen Ted

Abstract excerpt

BACKGROUND: The incidence of multidrug-resistant tuberculosis (MDR-TB) remains critically high in countries of the former Soviet Union, where >20% of new cases and >50% of previously treated cases have resistance to rifampin and isoniazid. Transmission of resistant strains, as opposed to resistance selected through inadequate treatment of drug-susceptible tuberculosis (TB), is the main driver of incident MDR-TB...

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Identifiers

PMID: 35192619
DOI: 10.1371/journal.pmed.1003933
PMCID: PMC8903246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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