Article
Identifying local foci of tuberculosis transmission in Moldova using a spatial multinomial logistic regression model.
EBioMedicine - 1 Apr 2024
Lan Yu, Crudu Valeriu, Ciobanu Nelly, Codreanu Alexandru, Chitwood Melanie H, Sobkowiak Benjamin, Warren Joshua L, Cohen Ted
Abstract excerpt
BACKGROUND: Multidrug resistant tuberculosis (MDR-TB) represents a major public health concern in the Republic of Moldova, with an estimated 31% of new and 56% of previously treated TB cases having MDR disease in 2022. A recent genomic epidemiology study of incident TB occurring in 2018 and 2019 found that 92% of MDR-TB was the result of transmission. The MDR phenotype was concentrated among two M. tuberculosis...
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