Article
The molecular characteristics of low-grade and high-grade areas in desmoplastic infantile astrocytoma/ganglioglioma.
Neuropathology and applied neurobiology - 1 Jun 2022
Chiang Jason, Li Xiaoyu, Jin Hongjian, Wu Gang, Lin Tong, Ellison David W
Abstract excerpt
AIMS: Desmoplastic infantile astrocytomas and gangliogliomas (DIA/DIGs) are rare brain tumours of infancy. A distinctive feature of their histopathology is a combination of low-grade and high-grade features. Most DIA/DIGs can be surgically resected and have a good prognosis. However, high-grade features often dominate recurrent tumours, some of which have a poor outcome. In this study, we test the hypothesis that...
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