Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway.

doi:10.1007/s00401-016-1639-9

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway.

Acta neuropathologica - 1 Mar 2017

Huse Jason T, Snuderl Matija, Jones David T W, Brathwaite Carole D, Altman Nolan, Lavi Ehud, Saffery Richard, Sexton-Oates Alexandra, Blumcke Ingmar, Capper David, Karajannis Matthias A, Benayed Ryma, Chavez Lukas, Thomas Cheddhi, Serrano Jonathan, Borsu Laetitia, Ladanyi Marc, Rosenblum Marc K

Abstract excerpt

Epileptogenic tumors affecting children and young adults are a morphologically diverse collection of neuroepithelial neoplasms that, as a group, exhibit varying levels of glial and/or neuronal differentiation. Recent advances in molecular profiling technology, including comprehensive DNA sequencing and methylation analysis, have enabled the application of more precise and biologically relevant classification...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD34

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epilepsy

Share to Glial Fibrillary Acidic Protein

Share to Mitogen-Activated Protein Kinases

Share to Neuroglia

Share to Oligodendroglioma

Share to Proto-Oncogene Mas

Share to Receptors, Fibroblast Growth Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 27812792
DOI: 10.1007/s00401-016-1639-9
PMCID: PMC5325850

Genes

BRAF
FGFR2
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway.PMID 27812792Read ↗

A newly diagnosed case of polymorphous low-grade neuroepithelial tumor of the young.Semantic proximity Read ↗

Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Scoping Review of Case Reports and Case SeriesSemantic proximity Read ↗

Clinical significance of molecular subgroups of polymorphous low-grade neuroepithelial tumor of the young (PLNTY): A small single institutional case series and integrated analysis.Semantic proximity Read ↗

MAPK pathway alterations in polymorphous low-grade neuroepithelial tumor of the young: diagnostic considerations.Semantic proximity Read ↗

Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR PathwaysSemantic proximity Read ↗

Systematic review and cumulative analysis of clinical properties of BRAF V600E mutations in PLNTY histological samples.Semantic proximity Read ↗

Pediatric and elderly polymorphous low-grade neuroepithelial tumor of the young: Typical and unusual case reports and literature review.Semantic proximity Read ↗

Systematic review and cumulative analysis of clinical properties of BRAF V600E mutations in PLNTY histological samplesSemantic proximity Read ↗

Genomic analysis of PLNTY-like tumor progression into epithelioid glioblastoma: a case report.Semantic proximity Read ↗

Pediatric Glial Tumors.Semantic proximity Read ↗

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.Semantic proximity Read ↗

Pediatric Brain TumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.