Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseases

24 Dec 2018

Abstract excerpt

INTRODUCTION: Mitochondrial-derived peptides (MDPs) are encoded within the mitochondrial genome. They signal within the cell or are released to act as autocrine/paracrine/endocrine cytoprotective factors playing a key role in the cellular stress response. The first reported and better characterized MDP is humanin (HN), which exerts robust protective effects against a myriad of cytotoxic stimuli in many cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GDF15 and Related Biomarkers
Share to Macrophage Migration Inhibitory Factor
Share to Nutrition and Health in Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30582721
DOI: 10.1080/14728222.2019.1559300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseasesPMID 30582721Read ↗

Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseasesSemantic proximity Read ↗

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markersSemantic proximity Read ↗

The emerging role of the mitochondrial-derived peptide humanin in stress resistanceSemantic proximity Read ↗

Humanin and Age-Related Diseases: A New Link?Semantic proximity Read ↗

Humanin: a harbinger of mitochondrial-derived peptides?Semantic proximity Read ↗

Mitochondrial-derived peptides in cardiovascular disease: Novel insights and therapeutic opportunitiesSemantic proximity Read ↗

Neuroprotective Action of Humanin and Humanin Analogues: Research Findings and PerspectivesSemantic proximity Read ↗

Mitochondria‑derived peptides: Promising microproteins in cardiovascular diseases (Review)Semantic proximity Read ↗

Mitochondrial-derived peptides in energy metabolismSemantic proximity Read ↗

MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related DiseasesSemantic proximity Read ↗

Role of humanin, a mitochondrial-derived peptide, in cardiovascular disordersSemantic proximity Read ↗

Mitochondrial-Derived Peptides in Diabetes and Its ComplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.