Article
Natural killer T cells and the regulation of asthma.
Mucosal immunology - 1 Sept 2009
Matangkasombut P, Pichavant M, Dekruyff R H, Umetsu D T
Abstract excerpt
A crucial role has been suggested for invariant natural killer T cells (iNKT) in regulating the development of asthma, a complex and heterogeneous disease characterized by airway inflammation and airway hyperreactivity (AHR). iNKT cells constitute a unique subset of T cells responding to endogenous and exogenous lipid antigens, rapidly secreting a large amount of cytokines, which amplify both innate and adaptive...
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