Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias.

eLife - 16 Feb 2022

Sujkowski Alyson, Richardson Kristin, Prifti Matthew V, Wessells Robert J, Todi Sokol V

Abstract excerpt

Endurance exercise is a potent intervention with widespread benefits proven to reduce disease incidence and impact across species. While endurance exercise supports neural plasticity, enhanced memory, and reduced neurodegeneration, less is known about the effect of chronic exercise on the progression of movement disorders such as ataxias. Here, we focused on three different types of ataxias, spinocerebellar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Exercise
Share to Oxidation-Reduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oxidoreductases

Share to Peptides

Share to Spinocerebellar Ataxias

Share to TOR Serine-Threonine Kinases

Share to Trinucleotide Repeat Expansion

Source

Open in PubMed Open full text

Identifiers

PMID: 35170431
DOI: 10.7554/eLife.75389
PMCID: PMC8871352

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias.PMID 35170431Read ↗

Endurance exercise ameliorates phenotypes in <i>Drosophila</i> models of Spinocerebellar AtaxiasSemantic proximity Read ↗

Systematic Phenotyping and Molecular Analysis of the Woozy Mouse: A Preclinical Model of Cerebellar Ataxia.Semantic proximity Read ↗

Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila.Semantic proximity Read ↗

Swim exercise in Caenorhabditis elegans extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegenerationSemantic proximity Read ↗

Progressive degeneration in a new Drosophila model of Spinocerebellar Ataxia type 7Semantic proximity Read ↗

SESN1 is a FOXO3 effector that counteracts human skeletal muscle ageingSemantic proximity Read ↗

Drosophila Endurance Training and Assessment of Its Effects on Systemic AdaptationsSemantic proximity Read ↗

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophySemantic proximity Read ↗

A genetic modifier suggests that endurance exercise exacerbates Huntington's disease.Semantic proximity Read ↗

Extension of Health Span and Life Span in Drosophila by S107 Requires the calstabin Homologue FK506-BP2.Semantic proximity Read ↗

Behavioral effects of SQSTM1/p62 overexpression in mice: support for a mitochondrial role in depression and anxiety.Semantic proximity Read ↗

Swim exercise in <i>C. elegans</i> extends neuromuscular and intestinal healthspan, enhances learning ability, and protects against neurodegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.