Article
High-resolution melting analyses for genetic variants in ARID5B and IKZF1 with childhood acute lymphoblastic leukemia susceptibility loci in Taiwan.
Blood cells, molecules & diseases - 1 Jan 2000
Lin Chien-Yu, Li Meng-Ju, Chang Jan-Gowth, Liu Su-Ching, Weng Tefu, Wu Kang-Hsi, Yang Shu-Fen, Huang Fu-Kuei, Lo Wan-Yu, Peng Ching-Tien
Abstract excerpt
BACKGROUND: Childhood acute lymphoblastic leukemia (ALL), a heterogeneous disease that includes multiple subtypes is defined by cell lineage and chromosome anomalies. Previous genome-wide association studies have reported several ARID5B and IKZF1 single nucleotide polymorphisms (SNPs) associated with the incidence of ALL. High-resolution melting (HRM) analysis is a rapid and convenient technique to detect SNPs;...
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