Significant association of XRCC4 single nucleotide polymorphisms with childhood leukemia in Taiwan.

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Significant association of XRCC4 single nucleotide polymorphisms with childhood leukemia in Taiwan.

Anticancer research - 1 Feb 2010

Wu Kang-Hsi, Wang Chung-Hsing, Yang Yung-Li, Peng Ching-Tien, Lin Wei-De, Tsai Fuu-Jen, Lin Dong-Tsamn, Bau Da-Tian

Abstract excerpt

BACKGROUND: The DNA repair gene XRCC4, a member of the protein family involved in non-homologous end-joining repair pathway, plays a major role in repairing DNA double-strand breaks. XRCC4 is important in maintaining the overall genome stability, and it is also thought to play a key role in human carcinogenesis. We investigated some novel polymorphic variants of XRCC4, including C-1622T (rs7727691), G-1394T...

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Identifiers

PMID: 20332465

Genes

XRCC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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