Article
Distinct metabolic hallmarks of WHO classified adult glioma subtypes.
Neuro-oncology - 1 Sept 2022
Björkblom Benny, Wibom Carl, Eriksson Maria, Bergenheim A Tommy, Sjöberg Rickard L, Jonsson Pär, Brännström Thomas, Antti Henrik, Sandström Maria, Melin Beatrice
Abstract excerpt
BACKGROUND: Gliomas are complex tumors with several genetic aberrations and diverse metabolic programs contributing to their aggressive phenotypes and poor prognoses. This study defines key metabolic features that can be used to differentiate between glioma subtypes, with potential for improved diagnostics and subtype targeted therapy. METHODS: Cross-platform global metabolomic profiling coupled with clinical,...
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