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Novel diabetes gene discovery through comprehensive characterization and integrative analysis of longitudinal gene expression changes

9 Feb 2022

Abstract excerpt

Type 2 diabetes is a complex, systemic disease affected by both genetic and environmental factors. Previous research has identified genetic variants associated with type 2 diabetes risk; however, gene regulatory changes underlying progression to metabolic dysfunction are still largely unknown. We investigated RNA expression changes that occur during diabetes progression using a two-stage approach. In our...

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PMID: 35157052
DOI: 10.1093/hmg/ddac039

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