Evaluating Multifactorial Contributors to Metabolic Syndrome in Western Mexico: The Role of Metabolic Age, Lifestyle, and IL32 rs45499297 Polymorphism.

doi:10.2174/0118715303424920251201091824

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Evaluating Multifactorial Contributors to Metabolic Syndrome in Western Mexico: The Role of Metabolic Age, Lifestyle, and IL32 rs45499297 Polymorphism.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Martínez-Perez Luz Andrea, González-Sánchez Grecia Denisse, Saraí Becerra-Ruiz Julieta, Martínez-Esquivias Fernando, Perez-Reyes Angel, Guzmán-Flores Juan Manuel

Abstract excerpt

BACKGROUND: Metabolic syndrome (MS) is characterized by a cluster of metabolic disorders that induce a state of chronic inflammation with multifactorial etiology. IL-32 is a cytokine associated with inflammatory conditions. The rs45499297 is a T/C promoter single-nucleotide polymorphism (SNP) of the IL32 gene, which may alter the production and activity of this cytokine. OBJECTIVES: This study examined the...

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Topics

Humans
Metabolic Syndrome
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Mexico

Cross-Sectional Studies

Male

Interleukins

Middle Aged

Adult

Life Style

Genetic Predisposition to Disease

Risk Factors

Age Factors

Genetic Association Studies

Source

Open in PubMed

Identifiers

PMID: 42257262
DOI: 10.2174/0118715303424920251201091824

Genes

IL32

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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