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SARS-CoV-2 Variants of Concern and Variants of Interest Receptor Binding Domain Mutations and Virus Infectivity.

Frontiers in immunology - 1 Jan 2022

Liu Haolin, Wei Pengcheng, Kappler John W, Marrack Philippa, Zhang Gongyi

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has lasted more than 2 years with over 260 million infections and 5 million deaths worldwide as of November 2021. To combat the virus, monoclonal antibodies blocking the virus binding to human receptor, the angiotensin converting enzyme 2 (ACE2), have been approved to treat the infected patients. Inactivated whole virus or the full-length...

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PMID: 35154144
DOI: 10.3389/fimmu.2022.825256
PMCID: PMC8828474

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