Article
Whole-genome sequencing of Kaposi sarcoma-associated herpesvirus (KSHV/HHV8) reveals evidence for two African lineages.
Virology - 1 Mar 2022
Moorad Razia, Juarez Angelica, Landis Justin T, Pluta Linda J, Perkins Megan, Cheves Avery, Dittmer Dirk P
Abstract excerpt
Kaposi sarcoma (KS)-associated herpesvirus (KSHV/HHV-8) was first sequenced from the body cavity (BC) lymphoma cell line, BC-1, in 1996. Few other KSHV genomes have been reported. Our knowledge of sequence variation for this virus remains spotty. This study reports additional genomes from historical US patient samples and from African KS biopsies. It describes an assay that spans regions of the virus that cannot...
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