Article
Sequence analyses of human herpesvirus-8 strains from both African human immunodeficiency virus-negative and -positive childhood endemic Kaposi's sarcoma show a close relationship with strains identified in febrile children and high variation in the K1 glycoprotein.
The Journal of general virology - 1 Dec 1998
Kasolo F C, Monze M, Obel N, Anderson R A, French C, Gompels U A
Abstract excerpt
Human herpesvirus-8 (HHV-8) DNA sequences have been identified in all forms of Kaposi's sarcoma (KS), a cancer found primarily in adult AIDS patients. We have identified HHV-8 strains in a rare human immunodeficiency virus (HIV)-negative form of KS, which is endemic in children in parts of sub-Sa...
Topics
- AIDS-Related Opportunistic Infections
- Adult
- Amino Acid Sequence
- Base Sequence
- Conserved Sequence
- DNA, Viral
- Endemic Diseases
- Fever
- Genes, Viral
- Genetic Variation
- Glycoproteins
- Herpesvirus 8, Human
- Humans