Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell surface expression of GRP78 and CXCR4 is associated with childhood high-risk acute lymphoblastic leukemia at diagnostics

11 Feb 2022

Abstract excerpt

Abstract Acute lymphocytic leukemia is the most common type of cancer in pediatric individuals. Glucose regulated protein (GRP78) is an endoplasmic reticulum chaperone that facilitates the folding and assembly of proteins and regulates the unfolded protein response pathway. GRP78 has a role in survival of cancer and metastasis and cell-surface associated GRP78 (sGRP78) is expressed on cancer cells but not in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Endoplasmic Reticulum Stress and Disease
Share to Genetics and Neurodevelopmental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35149705
DOI: 10.1038/s41598-022-05857-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell surface expression of GRP78 and CXCR4 is associated with childhood high-risk acute lymphoblastic leukemia at diagnosticsPMID 35149705Read ↗

High proportion of CD34+/CD38-cells is positively correlated with poor prognosis in newly diagnosed childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Proteomics in Childhood Acute Lymphoblastic Leukemia: Challenges and OpportunitiesSemantic proximity Read ↗

Cysteine and glycine-rich protein 2 (CSRP2) transcript levels correlate with leukemia relapse and leukemia-free survival in adults with B-cell acute lymphoblastic leukemia and normal cytogeneticsSemantic proximity Read ↗

Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancerSemantic proximity Read ↗

Proteomic analysis of cerebrospinal fluid in pediatric acute lymphoblastic leukemia patients: a pilot studySemantic proximity Read ↗

GRP78 promotes stemness in normal and neoplastic cellsSemantic proximity Read ↗

Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological DisordersSemantic proximity Read ↗

Therapeutic targeting of IL-7Rα signaling pathways in ALL treatmentSemantic proximity Read ↗

Roles of GRP78 in physiology and cancerSemantic proximity Read ↗

Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiPSemantic proximity Read ↗

Aberrant phenotypes in childhood and adult acute leukemia and its association with adverse prognostic factors and clinical outcome.Semantic proximity Read ↗

Biological characteristics of CD7(+) acute leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.