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Broadly Reactive Real-Time RT-PCR Assay for the Detection of Hepatitis E Virus and Simultaneous Genotyping by Single Nucleotide Polymorphism Analysis.

Microbiology spectrum - 23 Feb 2022

Ishida Setsuko, Yoshizumi Shima, Sakata Hidekatsu, Matsubayashi Keiji

Abstract excerpt

Hepatitis E virus (HEV) infection is a global public health concern. Although HEV infection is usually asymptomatic and self-limiting, extrahepatic manifestations and chronic infections in immunocompromised patients have been described. HEV strains infecting humans have been classified into four main genotypes. In this study we have developed and validated a novel sensitive real-time RT-PCR assay for the...

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Identifiers

PMID: 35138152
DOI: 10.1128/spectrum.01912-21
PMCID: PMC8826742

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