Article
Advanced sequencing approaches detected insertions of viral and human origin in the viral genome of chronic hepatitis E virus patients.
Scientific reports - 2 Feb 2022
Papp C-Patrick, Biedermann Paula, Harms Dominik, Wang Bo, Kebelmann Marianne, Choi Mira, Helmuth Johannes, Corman Victor M, Thürmer Andrea, Altmann Britta, Klink Patrycja, Hofmann Jörg, Bock C-Thomas
Abstract excerpt
The awareness of hepatitis E virus (HEV) increased significantly in the last decade due to its unexpectedly high prevalence in high-income countries. There, infections with HEV-genotype 3 (HEV-3) are predominant which can progress to chronicity in immunocompromised individuals. Persistent infection and antiviral therapy can select HEV-3 variants; however, the spectrum and occurrence of HEV-3 variants is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.