Article
Hepatitis E virus: Whole genome sequencing as a new tool for understanding HEV epidemiology and phenotypes.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2021
Davis Christopher A, Haywood Becky, Vattipally Sreenu, Da Silva Filipe Ana, AlSaeed Mariam, Smollet Katherine, Baylis Sally A, Ijaz Samreen, Tedder Richard S, Thomson Emma C, Abdelrahman Tamir T
Abstract excerpt
Hepatitis E Virus (HEV) is emerging as a public health concern across Europe and tools for complete genome data to aid epidemiological and virulence analysis are needed. The high sequence heterogeneity observed amongst HEV genotypes has restricted most analyses to subgenomic regions using PCR-based methods, which can be unreliable due to poor primer homology. We designed a panel of custom-designed RNA probes...
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