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Construction and characterization of two SARS‐CoV‐2 minigenome replicon systems

9 Feb 2022

Abstract excerpt

The ongoing COVID-19 pandemic severely impacts global public health and economies. To facilitate research on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virology and antiviral discovery, a noninfectious viral replicon system operating under biosafety level 2 containment is warranted. We report herein the construction and characterization of two SARS-CoV-2 minigenome replicon systems. First, we...

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PMID: 35137972
DOI: 10.1002/jmv.27650

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