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Article

Radiomics Strategy for Molecular Subtype Stratification of Lower-Grade Glioma: Detecting IDH and TP53 Mutations Based on Multimodal MRI.

Journal of magnetic resonance imaging : JMRI - 1 Oct 2018

Zhang Xi, Tian Qiang, Wang Liang, Liu Yang, Li Baojuan, Liang Zhengrong, Gao Peng, Zheng Kaizhong, Zhao Bofeng, Lu Hongbing

Abstract excerpt

BACKGROUND: Noninvasive detection of isocitrate dehydrogenase (IDH) and TP53 mutations are meaningful for molecular stratification of lower-grade gliomas (LrGG). PURPOSE: To explore potential MRI features reflecting IDH and TP53 mutations of LrGG, and propose a radiomics strategy for detecting them. STUDY TYPE: Retrospective, radiomics. POPULATION/SUBJECTS: A total of 103 LrGG patients were separated into...

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Source

Identifiers

PMID: 29394005
DOI: 10.1002/jmri.25960

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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