Article
An encodable multiplex microsphere-phase amplification sensing platform detects SARS-CoV-2 mutations.
Biosensors & bioelectronics - 1 May 2022
Zhong Zecheng, Wang Jin, He Shuizhen, Su Xiaosong, Huang Weida, Chen Mengyuan, Zhuo Zhihao, Zhu Xiaomei, Fang Mujin, Li Tingdong, Zhang Shiyin, Ge Shengxiang, Zhang Jun, Xia Ningshao
Abstract excerpt
SARS-CoV-2 variants of concern (VOCs) contain several single-nucleotide variants (SNVs) at key sites in the receptor-binding region (RBD) that enhance infectivity and transmission, as well as cause immune escape, resulting in an aggravation of the coronavirus disease 2019 (COVID-19) pandemic. Emerging VOCs have sparked the need for a diagnostic method capable of simultaneously monitoring these SNVs. To date, no...
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