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Amplification‐ and Enzyme‐Free Magnetic Diagnostics Circuit for Whole‐Genome Detection of SARS‐CoV‐2 RNA

6 May 2024

Abstract excerpt

Abstract Polymerase chain reaction (PCR) requires thermal cycling and enzymatic reactions for sequence amplification, hampering their applications in point‐of‐care (POC) settings. Magnetic bioassays based on magnetic particle spectroscopy (MPS) and magnetic nanoparticles (MNPs) are isothermal, wash‐free, and can be quantitative. Realizing them amplification‐ and enzyme‐free on a benchtop device, they will become...

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PMID: 38709072
DOI: 10.1002/cbic.202400251

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