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Mutation of D201G near the receptor binding site significantly drives antigenic drift of circulating H9N2 subtype avian influenza virus.

Transboundary and emerging diseases - 1 Nov 2022

Xia Jing, Luo Yu-Wen, Dong Meng-Yi, Li Yong-Xin, Wang An-Dong, Li Nian-Ling, Shen Yu-Xi, Li Shu-Yun, Cui Min, Han Xin-Feng, Yu Song-Cheng, Li Min, Huang Yong

Abstract excerpt

The H9N2 subtype of avian influenza virus (H9N2 AIV) has caused significant losses in chicken flocks throughout China. Our previous research has shown that field isolates of H9N2 underwent antigenic drift to evolve into distinct groups with significant antigenic divergence from the commercially available vaccines. The present study sought to identify which single mutations that have naturally appeared in isolates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36151953
DOI: 10.1111/tbed.14707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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