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Toll- like receptor 2 polymorphism and IL-6 profile in relation to disease progression in chronic HBV infection: a case control study in Egyptian patients.

Clinical and experimental medicine - 1 Feb 2023

Elbrolosy Asmaa M, Elabd Naglaa S, ElGedawy Gamalat A, Abozeid Mai, Abdelkreem Mervat, Montaser Belal, Eed Emad M, Elhamouly Moamena S

Abstract excerpt

Chronic hepatitis B (CHB) has a wide range of outcomes depending on host immune responses mainly Toll-like receptors (TLRs) signaling and released cytokines. Toll-like receptor 2 (TLR2) single nucleotide polymorphisms (SNPs) and interleukin 6 (IL-6) may influence the course of CHB. We aimed to elucidate the relation between TLR-2 polymorphism, IL-6 profile, and CHB progression. We analyzed TLR-2 polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35119591
DOI: 10.1007/s10238-022-00792-6
PMCID: PMC9939497

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