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Article

Fast, low-memory detection and localization of large, polymorphic inversions from SNPs.

PeerJ - 1 Jan 2022

Nowling Ronald J, Fallas-Moya Fabian, Sadovnik Amir, Emrich Scott, Aleck Matthew, Leskiewicz Daniel, Peters John G

Abstract excerpt

BACKGROUND: Large (>1 Mb), polymorphic inversions have substantial impacts on population structure and maintenance of genotypes. These large inversions can be detected from single nucleotide polymorphism (SNP) data using unsupervised learning techniques like PCA. Construction and analysis of a feature matrix from millions of SNPs requires large amount of memory and limits the sizes of data sets that can be...

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PMID: 35116204
DOI: 10.7717/peerj.12831
PMCID: PMC8784018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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