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Article

Detecting inversions with PCA in the presence of population structure.

PloS one - 1 Jan 2020

Nowling Ronald J, Manke Krystal R, Emrich Scott J

Abstract excerpt

Chromosomal inversions can lead to reproductive isolation and adaptation in insects such as Drosophila melanogaster and the non-model malaria vector Anopheles gambiae. Inversions can be detected and characterized using principal component analysis (PCA) of single nucleotide polymorphisms (SNPs). To aid in developing such methods, we formed a new benchmark derived from three publicly-available insect data. We then...

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Identifiers

PMID: 33119626
DOI: 10.1371/journal.pone.0240429
PMCID: PMC7595445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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