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Article

REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis

3 Feb 2022

Abstract excerpt

REV1 is the central member of the family of TLS polymerases, which participate in various DNA damage repair and tolerance pathways and play a significant role in maintaining genomic stability. However, the role of REV1 in tumors is rarely reported. In this study, we found that the expression of REV1 was significantly upregulated in lung cancer tissues compared with matched adjacent tissues and was associated with...

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PMID: 35115490
DOI: 10.1038/s41419-022-04567-5

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