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Article

REV1 Inhibition Enhances Radioresistance and Autophagy

2021-09-13

Abstract excerpt

Cancer therapy resistance is a persistent clinical challenge. Recently, inhibition of the mutagenic translesion synthesis (TLS) protein REV1 was shown to enhance tumor cell response to chemotherapy by triggering senescence hallmarks. These observations suggest REV1’s important role in determining cancer cell response to chemotherapy. Whether REV1 inhibition would similarly sensitize cancer cells to radiation...

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Identifiers and source

Literature Corpus work
41899eba-61fc-578d-863f-f544ed75277d
DOI
10.20944/preprints202109.0202.v1
Open publication

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REV1 Inhibition Enhances Radioresistance and AutophagyDOI 10.20944/preprints202109.0202.v1
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