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Article

Functional genetic variants in complement component 7 confer susceptibility to gastric cancer.

PeerJ - 1 Jan 2022

Wang Siyue, Hu Wenqian, Xie Yuning, Wu Hongjiao, Jia Zhenxian, Zhang Zhi, Zhang Xuemei

Abstract excerpt

BACKGROUND: Complement system plays an important role in innate immunity which involved in the changes tumor immune microenvironment by mediating the inflammatory response. This study aims to explore the relationship between complement component 7 (C7) polymorphisms and the risk of gastric cancer (GC). MATERIALS AND METHODS: All selected SNPs of C7 were genotyped in 471 patients and 471 controls using the...

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Identifiers

PMID: 35111412
DOI: 10.7717/peerj.12816
PMCID: PMC8781313

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