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Article

Diversity of hepatitis E virus genotype 3.

Reviews in medical virology - 1 Sept 2018

Nicot Florence, Jeanne Nicolas, Roulet Alain, Lefebvre Caroline, Carcenac Romain, Manno Maxime, Dubois Martine, Kamar Nassim, Lhomme Sébastien, Abravanel Florence, Izopet Jacques

Abstract excerpt

Hepatitis E virus genotype 3 (HEV-3) can lead to chronic infection in immunocompromised patients, and ribavirin is the treatment of choice. Recently, mutations in the polymerase gene have been associated with ribavirin failure but their frequency before treatment according to HEV-3 subtypes has not been studied on a large data set. We used single-molecule real-time sequencing technology to sequence 115 new...

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PMID: 29939461
DOI: 10.1002/rmv.1987

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