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Article

Casein kinases are required for the stability of the glucose-sensing receptor Rgt2 in yeast.

Scientific reports - 31 Jan 2022

Kim Jeong-Ho, Bloor Daniel, Rodriguez Rebeca, Mohler Emma, Mailloux Levi, Melton Sarah, Jung Dajeong

Abstract excerpt

In yeast, glucose induction of HXT (glucose transporter gene) expression is achieved via the Rgt2 and Snf3 glucose sensing receptor (GSR)-mediated signal transduction pathway. The membrane-associated casein kinases Yck1 and Yck2 (Ycks) are involved in this pathway, but their exact role remains unclear. Previous work suggests that the Ycks are activated by the glucose-bound GSRs and transmit the glucose signal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35102180
DOI: 10.1038/s41598-022-05569-1
PMCID: PMC8803954

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