Article
Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae.
The EMBO journal - 1 May 1998
Ozcan S, Dover J, Johnston M
Abstract excerpt
How eukaryotic cells sense availability of glucose, their preferred carbon and energy source, is an important, unsolved problem. Bakers' yeast (Saccharomyces cerevisiae) uses two glucose transporter homologs, Snf3 and Rgt2, as glucose sensors that generate a signal for induction of expression of genes encoding hexose transporters (HXT genes). We present evidence that these proteins generate an intracellular...
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